LYMPHOGRANULOMA VENEREUM – DEFINITION; DIAGNOSIS AND INVESTIGATION
Lymphogranuloma venereum (LGV) is caused by Chlamydia trachomatis (serotypes LI, L2 and L3) and is characterised by inguinal lymphadenopathy (buboes) and rectal strictures. Highest prevalence is in the tropics. LGV is rarely diagnosed in Australia but may be seen in people who have come from Asia or Africa. It may be underreported and misdiagnosed because the disease is not suspected.
This diagnosis should be considered if there is a history of a primary lesion with subsequent development of lymphadenopathy. The diagnosis may be confirmed by serological tests (titre 1:128 in complement fixation test or 1:512 in microimmunofluoresccnce tests) or by culture of bubo pus or from genital lesions.
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